The estuary was named Santa Lucia by Portuguese explorers who first reached it in 1576. Today Santa Lucia is the name of the Ezemvelo KZN Wildlife boat that operates 1.5-hour cruises on the Estuary three to four times a day. One or two private operators offer similar cruises. You'll get to see lots and lots of hippos, some crocodiles, various water birds and often African Fish Eagle. If you only have limited time to spend in town we suggest that you opt for this activity.

The town is also home to the St. Lucia Crocodile Centre. Originally established to help replenish the crocodile population of Lake St. Lucia and its estuary it now also fulfils an educational function. Visitors to the centre can view all the African species of crocodiles, a wide variety of snakes, other animals found along the shores of the Lake and a host of other information about the area's ecology.

There's a short hiking trail along the shores of the estuary although caution should be taken due to the presence of crocodiles. Swimming in the lake and estuary is prohibited for the same reason. The town offers a large collection of middle class guesthouses and B&B's. There are also two Ezemvelo campsites.